This updated Second Edition offers a deeper, more comprehensive exploration of advanced medical concepts in dialysis treatment and care. Written for healthcare professionals, patients, caregivers, and students alike, the book aims to improve quality outcomes for individuals undergoing dialysis by addressing the complex realities of the disease process, moving beyond clinical procedure to address the holistic journey of kidney disease. The book provides a vital resource for navigating the complexities of chronic kidney disease and dialysis. It translates current evidence-based research into practical knowledge. Zuleta covers essential topics from foundational kidney function and the nuances of different dialysis modalities to managing comorbidities and improving patient quality of life. A core message of the book is the power of knowledge to transform patient outcomes through a collaborative model of care where informed healthcare professionals and empowered patients work together as partners.