This authoritative text begins with an introduction to basic microarray technology. The author then provides clear explanations of the conceptual and theoretical basis of this technology, followed by thorough and multi-disciplinary coverage of modern and emerging applications. The coverage includes chapters on microarray informatics, gene expression profiling, genetic diagnostics, and novel microarray technologies.
Microarrays, widely recognized as the next revolution in molecular biology, enable scientists to analyze genes, proteins and other biological molecules on a genomic scale. This emerging technology, used in more than 10,000 laboratories already, is having an enormous impact in all areas of biomedicine and across the agricultural, biotechnology, and pharmaceutical industries. Mark Schena's Microarray Analysis is the first textbook in this revolutionary new field of study.
This comprehensive and multidisciplinary text begins with an introduction to microarray analysis, and explores basic chemistry, biochemistry, and genomics. Separate chapters are devoted to surface chemistry, target and probe preparation, microarray manufacture and detection, and data analysis and modeling. Methodology, cleanroom technology, gene expression profiling, genetic screening and diagnostics, and novel technologies round out this classic textbook. Microarray Analysis provides any science student or professional all the tools required to understand this revolutionary technology.
* Rapidly teaches students the fundamentals of microarrays
* Describes protein microarrays and other rapidly advancing forefronts
* Builds a conceptual foundation for the entire field
* Presents commercial opportunities in microarray science
* Emphasizes the exciting clinical applications of microarrays